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Table 2 Results of shake flask fermentation of different Recombinant strains

From: Promoting cytidine biosynthesis by modulating pyrimidine metabolism and carbon metabolic regulatory networks in Bacillus subtilis

Strains

OD600

Cytidine (g/L)

Yield (g/g glucose)

Productivity (g/L/h)

BSNX2

10.57 ± 0.35

0.32 ± 0.02

0.014 ± 0.002

0.007 ± 0.001

BSNX3

10.21 ± 0.27

0.67 ± 0.04**

0.031 ± 0.004**

0.014 ± 0.002**

BSNX4

8.05 ± 0.19**

0.50 ± 0.02*

0.023 ± 0.002*

0.010 ± 0.001**

BSNX4-DM

11.23 ± 0.53**

2.03 ± 0.05**

0.078 ± 0.001**

0.043 ± 0.005**

  1. Significance represents the difference between each recombinant strain and its starting strain (BSNX3 vs. BSNX2, BSNX4 vs. BSNX3, BSNX4-DM vs. BSNX3)
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Microbial Cell Factories

ISSN: 1475-2859

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