Production and characterization of exopolysaccharides from Pseudomonas aeruginosa AG01 with some medical potential applications

Table 6 Effect of purified EPS produced by P. aeruginosa as an anticancer against different cell lines (Vero, PC3, and MCF7)

Cell line	Conc. of purified EPS µg/ml	Mean O. D	ST. E	Viability %	Toxicity %	IC50 µg/ml
	Control	0.696	0.003	100	0
Vero	1000	0.039	0.001	5.65	94.35	590.71 ± 5.06
	500	0.357	0.005	51.29	48.71
	250	0.666	0.007	95.74	4.26
	125	0.695	0.002	99.81	0.19
	62.5	0.695	0.001	99.81	0.19
	31.25	0.695	0.002	99.86	0.14
PC3	Control	0.667	0.0029	100	0	156.41 ± 1.12
	1000	0.019	0.0006	2.85	97.15
	500	0.019	0.0003	2.90	97.10
	250	0.024	0.0019	3.65	96.35
	125	0.415	0.0046	62.77	37.23
	62.5	0.665	0.0015	99.70	0.300
	31.25	0.666	0.0021	99.85	0.150
MCF7	Control	0.751	0.003	100	0	114.6 ± 1.46
	1000	0.022	0.001	2.97	97.03
	500	0.028	0.001	3.77	96.23
	250	0.110	0.007	14.60	85.40
	125	0.332	0.004	44.25	55.75
	62.5	0.599	0.004	79.72	20.28
	31.25	0.751	0.001	100	0

ISSN: 1475-2859