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Table 1 Experimental factors and level of minimum and maximum range for statistical screening using central composite design (CCD)

From: Nutritional optimization for bioprocess production of staphyloxanthin from Staphylococcus aureus with response surface methodology: promising anticancer scaffold targeting EGFR inhibition

Factors

Variables

Unit

Production level

Minimum (-1)

Intermediate (0)

Maximum (+ 1)

X1

Temperature

-

30

37

44

X2

pH

-

5

7

9

X3

Mannitol

g %

0.5

1.5

2.5

X4

Peptone

g %

0.5

1.5

2.5

X5

Incubation time

hr

24

48

72

X6

ZnCl2

mM

10

20

30