Fig. 5

Proteomic analysis of strains with increased laccase activity. (A) Heatmap representing the Pearson correlation of measured protein intensities of indicated strains compared to all other collected proteomes. (B) Principal component analysis of the individual proteomes of the 20 hit strains and BY4741. The proteomes form 5 groups, highlighted by coloured ovals. (C) Stacked bar chart of significantly up and downregulated proteins from each strain after comparing with the reference BY4741 strain. (D) Volcano plot of up and downregulated proteins in CLIB649 compared to BY4741. Proteins involved in protein glycosylation highlighted in black, and those significantly up or downregulated labeled