Fig. 2

L. gasseri LGV03 altered gene expression and pathways in zebrafish. (A) The volcano plot in comparison of two groups of zebrafish. (B) Heat map of the differentially expressed genes (DEGs) compared between group B and M. (C) mRNA expression of CLCA1, PLAC8.1 and ZNF1162 in zebrafish by RNA-Seq. (D) mRNA gene expression of CLCA1, PLAC8.1 in zebrafish after treatment of vinorelbine and L. gasseri LGV03. (E) Go analysis comparison of group B and M. (F) Analysis of DEGs KEGG pathway enrichment in groups B and M. B: L. gasseri LGV03 plus Vinorelbine group, M: Vinorelbine group