Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria

Table 2 Variations in the biofilm formation profiles in S. aureus and P. aeuroginosa before and after treatment with different concentrations of AgNPs

S. aureus				P. aeuroginosa
Before treatment Median (range)	After treatment Median (range)	Wilcoxon signed rank test	p value	Before treatment Median (range)	After treatment Median (range)	Wilcoxon signed rank test	p value
At sliver concentration 250		Z = 5.28	<0.0001	At sliver concentration 250		Z = 6.03	<0.0001
3 (3:3)	0 (0:3)	Z = 5.28	<0.0001	3 (2:3)	0 (0:3)	Z = 6.03	<0.0001
At sliver concentration 125		Z = 5.43	<0.0001	At sliver concentration 125		Z = 6.06	<0.0001
3 (3:3)	0 (0:2)	Z = 5.43	<0.0001	3 (2:3)	0 (0:3)	Z = 6.06	<0.0001
At sliver concentration 62.5		Z = 5.61	<0.0001	At sliver concentration 62.5		Z = 6.07	<0.0001
3 (3:3)	0 (0:3)	Z = 5.61	<0.0001	3 (2:3)	0 (0:3)	Z = 6.07	<0.0001
At sliver concentration 31.25		Z = 5.64	<0.0001	At sliver concentration 31.25		Z = 5.99	<0.0001
3 (3:3)	0 (0:2)	Z = 5.64	<0.0001	3 (2:3)	0 (0:3)	Z = 5.99	<0.0001
At sliver concentration 15.6		Z = 5.64	<0.0001	At sliver concentration 15.6		Z = 5.85	<0.0001
3 (3:3)	0 (0:2)	Z = 5.64	<0.0001	3 (2:3)	0 (0:3)	Z = 5.85	<0.0001
At sliver concentration 7.8		Z = 5.56	<0.0001	At sliver concentration 7.8		Z = 5.86	<0.0001
3 (3:3)	0 (0:1)	Z = 5.56	<0.0001	3 (2:3)	0 (0:3)	Z = 5.86	<0.0001
At sliver concentration 3.9		Z = 5.56	<0.0001	At sliver concentration 3.9		Z = 5.74	<0.0001
3 (3:3)	0 (0:2)	Z = 5.56	<0.0001	3 (2:3)	1 (0:3)	Z = 5.74	<0.0001
At sliver concentration 1.9		Z = 5.23	<0.0001	At sliver concentration 1.9		Z = 5.26	<0.0001
3 (3:3)	1 (0:3)	Z = 5.23	<0.0001	3 (2:3)	2 (0:3)	Z = 5.26	<0.0001
At sliver concentration 0.9		Z = 4.75	<0.0001	At sliver concentration 0.9		Z = 3.16	0.002
3 (3:3)	2 (0:3)	Z = 4.75	<0.0001	3 (2:3)	3 (0:3)	Z = 3.16	0.002

ISSN: 1475-2859