Fig. 1
From: The metabolic engineering of Escherichia coli for the high-yield production of hypoxanthine
Metabolic pathway diagram of hypoxanthine. The blue arrow represents the introduction of heterologous genes, the yellow arrow represents the weakening gene, the green arrow represents the overexpressed gene, and the red arrow represents the deletion of related genes. purF, glnA, and pur (FDNTSQLMKECB) were from Bacillus subtilis, and isn1 were from Saccharomyces cerevisiae