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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Metabolic engineering of Corynebacterium crenatum for enhanced L-tyrosine production from mannitol and glucose

Fig. 1

Metabolic pathway of tyrosine synthesis in Corynebacterium crenatum. Red font indicates that the gene is overexpressed. The green “x” indicates that the gene has been knocked out. mtlT encodes mannitol transporter; aroG encodes 3-deoxy-7-phosphoheptulonate synthase from E. coli; aroB encodes 3-dehydroquinate synthase; aroD encodes putative 3-dehydroquinate dehydratase; aroE encodes shikimate dehydrogenase; qsuB encodes 3-dehydroshikimate dehydratase; qsuD encodes shikimate dehydrogenase; trpE encodes anthranilate synthase; pheA encodes prephenate dehydratase; tyrA encodes arogenate dehydrogenase from E. coli; aroP encodes aromatic amino acid transport protein; tyrP encodes tyrosine permease; pyk encodes pyruvate kinase; ppsA encodes phosphoenolpyruvate synthase; mtlD encodes mannitol dehydrogenase; mtlR encodes mannitol repressor; pfkB encodes fructose-1-phosphate kinase; DAHP: 3-deoxy-7-phosphoheptulonate; DHQ: 3-dehydroquinic acid; DHS: 3-dehydroshikimic acid; SA: shikimic acid; CA: chorismate acid

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Microbial Cell Factories

ISSN: 1475-2859

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