Fig. 7
From: Robustness quantification of a mutant library screen revealed key genetic markers in yeast
Fitness and robustness in the three perturbation spaces combined together (CPS, BPS, and LHPS). The y-axis (0;0.2) represents the maximum specific growth rate (1/h) across all strains (controls and mutants with single gene deletions) and perturbations (n = 144), with the black line in the boxplot indicating the median of the distribution and the white dot indicating the mean. Significant difference between the parental strain and the mutants is denoted by p-values obtained from Wilcox tests (****p < 0.0001, not significant scores are omitted). Robustness of the maximum growth rate is shown by dots on the y-axis (− 0.2;0), while the horizontal black line denotes robustness and fitness of the CEN.PK113-7D parental strain. Groups are colored differently based on analysis of the reference dataset (HR: highest robustness score different from zero; R0HF: robustness equal to zero and highest fitness score; LR: lowest robustness score; controls: CEN.PK113-7D parental and Ethanol Red)