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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Bioprocessing of camptothecin from Alternaria brassicicola, an endophyte of Catharanthus roseus, with a strong antiproliferative activity and inhibition to Topoisomerases

Fig. 4

Cell cycle and apoptosis of UO-31 in response to CPT purified A. brassicicola CPT. The cell cycle of UO-31 cells without CPT (A), and treated with A. brassicicola CPT (B), and the overall cellular growth arrest (C) in response CPT compared to control. The apoptotic analysis of UO-31 cells by Annexin-V-PI without CPT (D), with A. brassicicola  CPT (E) and the overall apoptotic ratios (F)

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