Fig. 6
From: Efficient production of guanosine in Escherichia coli by combinatorial metabolic engineering
Redistributing the metabolic flux of EMP and ED and redox cofactor rebalancing for the accumulation of guanosine. (a) Schematic of the EMP and ED pathways; (b) Schematic of redox cofactor rebalancing; (c) Increased guanosine production by downregulating the metabolic flux of EMP and ED and redox cofactor rebalancing. All data represent the mean ± s.d. (n = 4 biologically independent samples). Error bars were analysed by Student’s t test (two-sample, two-tailed; ns represents no significant difference)