Fig. 3

PUFA formation pathways in microorganisms, based on traditional fatty acid synthase pathway. Fatty acid residues are synthesized by the FAS-enzyme complex from malonyl-CoA and acetyl-CoA. PUFAs are categorized into two groups, named as n-3 and n-6 series, depending on the location of the double bond with respect to the terminal -CH3 group. PUFA pathway in M. circinelloides has been highlighted