Fig. 3
From: Cell-based high-throughput screening of polysaccharide biosynthesis hosts
High-throughput screening of polysaccharide biosynthesis hosts based on biosensors in vivo. This strategy relies on linking the production of a fluorescent protein to the intracellular concentration of a target metabolite that is associated with the cell’s ability to synthesize polysaccharide. Then, high-yield strains can be enriched through FACS and sequenced