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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Disruption or reduced expression of the orotidine-5′-decarboxylase gene pyrG increases citric acid production: a new discovery during recyclable genome editing in Aspergillus niger

Fig. 5

Citric acid production of pyrG titratable expression mutant in 5 L bioreactor. Citric acid titers of pyrG titratable expression mutant under 0 and 20 μg/mL Dox were compared with its parent strains in the 5 L bioreactor. 1 × 105 spores/mL were inoculated in 3 L citrate fermentation (CitFM) media at 34 °C in the dark for 124 h. The extracellular citric acid was determined by the method of HPLC. Control, the parent strains D353; XMD1.6, the pyrG conditional expression mutants

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Microbial Cell Factories

ISSN: 1475-2859

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