Fig. 1

Schematic representation and distributions of fluxes in central carbon metabolism. Schematic representation of the average flux of 43 strains. The colors of the lines are representative of the average flux values across all strains expressed as a percentage of the glucose input and represented by a gradient of color from yellow to red. The average flux values ± the standard deviation are indicated by blue numbers for selected and representative reactions. Distribution of flux values for several selected reactions (a–n). The fluxes are normalized by the average flux of each reaction and therefore are represented by between 0 and 3, where 1 is the average flux. The reactions constrained by experimental data are indicated in red, and those predicted by the model are in blue