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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Characterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: generation of a novel improved derivative

Fig. 5

Proposed biosynthesis pathway of PM100117 and PM100118 naphthoquinone moiety. LD loading domain, M1 extension module. Polyketide synthase domains are as follows KS ketosynthase, AT acyltransferase, KR ketoreductase, DH dehydratase, ACP acyl-carrier-protein, CAL CoA ligase, KSIII 3-oxoacyl-ACP synthase III

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Microbial Cell Factories

ISSN: 1475-2859

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