Fig. 6

Optimization of 11β-hydroxy-manoyl oxide production in yeast cells. a Bar chart depicting the titers of manoyl oxide and 11β-hydroxy-manoyl oxide obtained using the different strains developed in this study. b Efficiency of conversion of manoyl oxide to 11β-hydroxy-manoyl oxide by CYP76AH24 in the different yeast strains developed. The efficiency of conversion is calculated as the ratio of 11β-hydroxy-manoyl oxide titer to the sum of manoyl oxide and 11β-hydroxy-manoyl oxide titres, expressed as percentage