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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Mechanism of imidazolium ionic liquids toxicity in Saccharomyces cerevisiae and rational engineering of a tolerant, xylose-fermenting strain

Fig. 1

Chemical genomic profiling of ionic liquids. For chemical genomic profiling a genome-wide set of deletion mutants are challenged with a specific compound or solvent control and grown as a pool for several generations. Mutant specific barcodes are then sequenced and compared to control conditions to determine mutants significantly responsive to the chemical stressor (chemical genetic interaction score), which are then used to predict mode of action and points for engineering tolerance

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Microbial Cell Factories

ISSN: 1475-2859

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