Fig. 1
From: From cyanochemicals to cyanofactories: a review and perspective
Strategies of genetic engineering for improvement of chemicals production from CO2 in cyanobacteria. Improvement of photosynthesis including enhancing light reactions (I), optimizing Rubisco to increase the efficiency of Calvin cycle (II) and disrupting photorespiration pathway to reduce photorespiration (III). Target pathway designs include blocking competing pathways and storages pathways (IV), and increasing expression level of key enzymes to drive more carbon flux towards target pathways, with the consideration of co-factor balance by using NADPH-dependent enzymes (V)