Fig. 1

Chemical structures. a Structure of cobalamin (1) molecule with the lower ligand DMBI (2) indicated by a dotted box. Adenine (3) is the lower ligand of the pseudovitamin form. R denotes possible upper ligands. b The reaction catalyzed by the BluB enzyme: formation of DMBI from FMNH2 (4). c The reaction catalyzed by the CobT enzyme: formation of α-RP (5) from DMBI and NaMN