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Table 2 Top10 of the genes differently expressed in S. cerevisiae in single-culture (Sc) and mixed-culture (Mc) fermentations, at the three fermentation stages (24, 48 and 96 h)

From: Genomic expression program of Saccharomyces cerevisiae along a mixed-culture wine fermentation with Hanseniaspora guilliermondii

ORF

Gene

Function

Fold change Sc/Mc

24 h

 YCL025C

AGP1

Low-affinity amino acid permease with broad substrate range

13.4

 YDR508C

GNP1

High-affinity glutamine permease

8.1

 YOL086 W-A

 

Molecular function unknown

5.7

 YHR021 W-A

ECM12

Putative protein of unknown function

5.3

 YKL183C-A

 

Putative protein of unknown function

5.1

 YOR348C

PUT4

Proline permease

4.8

 YDR130C

FIN1

Spindle pole body-related intermediate filament protein

4.6

 YBL042C

FUI1

High affinity uridine permease

4.5

 YAL037C-A

 

Putative protein of unknown function 

4.4

 YBL052C

SAS3

Histone acetyltransferase activity

4.0

 YHR044C

DOG1

2-deoxyglucose-6-phosphate phosphatase

−11.8

 YDR018C

 

Transferase activity, transferring acyl groups

−8.9

 YPL258C

THI21

Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis

−7.9

 YDL021 W

GPM2

Molecular function unknown

−7.1

 YHR043C

DOG2

2-deoxyglucose-6-phosphate phosphatase

−6.7

 YCR020C

PET18

Protein of unknown function

−6.1

YLR176C

RFX1

Major transcriptional repressor of DNA-damage-regulated genes

−6.1

 YHL048C-A

 

Putative protein of unknown function

−5.9

 YOL055C

THI20

Trifunctional enzyme of thiamine biosynthesis, degradation and salvage

−5.6

 YHR076 W

PTC7

Type 2C serine/threonine protein phosphatase (PP2C)

−5.5

48 h

 YLR142 W

PUT1

Proline oxidase involved in utilization of proline as sole nitrogen source

55.3

 YJR152 W

DAL5

Allantoate permease

52.7

 YKR039 W

GAP1

General amino acid permease

25.3

 YMR107 W

SPG4

Molecular function unknown

23.3

 YMR175 W

SIP18

Phospholipid binding

21.2

 YMR118C

 

Putative mitochondrial inner membrane protein of unknown function

20.3

 YPR194C

OPT2

Oligopeptide transporter

18.3

 YCR098C

GIT1

Plasma membrane permease; mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate

17.4

 YHL016C

DUR3

Plasma membrane transporter for both urea and polyamines

15.4

 YCL064C

CHA1

Catabolic l-serine (l-threonine) deaminase

13.8

 YMR095C

SNO1

Protein of unconfirmed function; involved in pyridoxine metabolism; expression is induced during stationary phase

−14.2

 YCL026C-A

FRM2

Type II nitroreductase, using NADH as reductant

−13.7

 YGL117 W

 

Putative protein of unknown function

−12.9

 YBR092C

PHO3

Acid phosphatase activity

−10.1

 YMR094 W

CTF13

Subunit of the CBF3 complex

−9.9

 YML116 W

ATR1

Multidrug efflux pump of the major facilitator superfamily

−8.2

 YML123C

PHO84

High-affinity inorganic phosphate (Pi) transporter

−8.0

 YLR372 W

SUR4

Elongase; involved in fatty acid and sphingolipid biosynthesis

−7.8

 YGL162 W

SUT1

Transcription factor of the Zn(II)2Cys6 family; positively regulates genes involved in sterol uptake under anaerobic conditions

−7.2

 YBR249C

ARO4

3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase

−6.9

96 h

 YEL061C

CIN8

Kinesin motor protein

86.2

 YJL051 W

IRC8

Bud tip localized protein of unknown function

43.0

 YJL148 W

RPA34

RNA polymerase I subunit A34.5

28.6

 YNL129 W

NRK1

Nicotinamide riboside kinase

27.6

 YLR265C

NEJ1

Protein involved in regulation of non homologous end joining

25.9

 YOR177C

MPC54

Component of the meiotic outer plaque

21.9

 YOR305 W

RRG7

Protein of unknown function

21.0

 YLR151C

PCD1

8-oxo-dGTP diphosphatase

21.0

 YKL011C

CCE1

Mitochondrial cruciform cutting endonuclease

21.0

 YDR523C

SPS1

Putative protein serine/threonine kinase

19.5

 YBR194 W

AIM4

Protein proposed to be associated with the nuclear pore complex

−4.5

 YOR090C

PTC5

Mitochondrial type 2C protein phosphatase (PP2C)

−3.6

 YGR213C

RTA1

Protein involved in 7-aminocholesterol resistance

−3.3

 YDR434 W

GPI17

Transmembrane protein

−3.2

 YBR111C

YSA1

Nudix hydrolase family member with ADP-ribose pyrophosphatase activity

−3.2

 YOL131 W

 

Putative protein of unknown function

−3.2

 YER061C

CEM1

Mitochondrial beta-keto-acyl synthase

−3.1

 YNR058 W

BIO3

7,8-diamino-pelargonic acid aminotransferase (DAPA)

−3.1

 YCL032 W

STE50

Adaptor protein for various signaling pathways

−3.0

 YOR353C

SOG2

Key component of the RAM signaling network

−3.0