Fig. 7

Measured vs. simulated CEN.PK auxotroph growth in fed-batch with variable feeding regime. Time series of measured microbial mass (times symbol), glucose (filled circle) and ethanol (open circle) data vs. model simulations (continuous lines). Dashed vertical lines represent the beginning of the feeding phase. The dotted lines in the middle and lower panels show the glucose feeding profile and the inhibitor simulated values respectively. Calibrated parameters for µ* were m1 = 0.1863, m2 = 0.1628 and m3 = 14.1092.